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President Obama on Wednesday ordered the Presidential Commission for the Study of Bioethical Issues to conduct a review of the rules regarding the protections of human subjects in research -- both studies conducted in the United States and abroad. He noted the recent revalations that the U.S. Public Health Service "conducted research on sexually transmitted diseases in Guatemala from 1946 to 1948 involving the intentional infection of vulnerable human populations. The research was clearly unethical. In light of this revelation, I want to be assured that current rules for research participants protect people from harm or unethical treatment, domestically as well as internationally." Obama's statement said that "[w]hile I believe the research community has made tremendous progress in the area of human subjects protection, what took place in Guatemala is a sobering reminder of past abuses." He asked for a report to be completed within nine months.